Black Plague By edward,p 1318 Gobi Desert 1326 Lower Volga River 1334 Lake Issyk Kul 1346 Crimea and Caucasus 1347 Messina, Sicily 1347 Constantinople 1347 Egypt 1347 Alexandria 1347 Italy and Greece 1348 Genoa, Venice 1348 Britain and Ireland 1349 Northern Europe 1349 Mecca 1351 Yemen 1353 Moscow