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Printing press invented by Johannes Gutenberg.
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Christopher Columbus lands in San Salvador
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Vasco da Gama makes the all water trip to In
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Ponce de Leon lands in Florida.
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German Monk Martin Luther nails his ninety-five theses to the church door
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Cortez conquers the Aztecs
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Pizarro conquers the Incas
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King Henry VIII breaks from the Roman Catholic Church and founds the Anglican Church
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Bartolome de Las Casa writes A Short Account of the Destruction of the Indies
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St. Augustine, Florida is founded (the oldest city in the US)
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Sir Walter Raleigh founds Roanoke Island off the coast of North Carolin
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Spanish Armada is defeated and England becomes Mistress of the Seas
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Samuel de Champlain founded Quebec
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Dutch West India Company sent settler to settle in New Netherlands (parts of New York, New Jersey, Delaware and Connecticut)
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Peter Minuit helped the Swedish found Ft. Christina on the Delaware River