Alexander the Great By Darius Loville 356 BCE Birth Alexander the great was born in 338 BCE led an army against a sacred band 336 BCE Alexanders father Phillip was assassinated by his bodyguard Pausanias 333 BCE Alexander and his men encountered a massive Persian army led by Darius the 3rd in the town of Issus 332 BCE Led the siege to heavily fortify the island of Tyre 331 BCE Faced Darius and his troops at Gaugamela 330 BCE Ordered the death of one of his most esteemed generals Pramerio 328 BCE Ordered the death of Cleitus 323 BCE Alexanders death 332 He amassed a large fleet breached the city’s walls