16th century By Maria Melis Palou Apr 22, 1451 Birth of Isabella I of Castile 1452 Birth of King Ferdinand II of Aragon Oct 19, 1469 Maarriage of the two Kings of spain( Isabella I and Ferdinant II) Jun 15, 1475 Union of the Aragon and Castile dynasty Sep 4, 1478 Implementation of the Inquisition in Castile. Jan 2, 1492 End of la Reconquista: Conquest of Granada Oct 12, 1492 Discovery of America Dec 19, 1496 Denomination of Catholic Monarchs Feb 24, 1500 Birth of Charles I of Spain Nov 26, 1504 Death of Isabella I of castile Jan 23, 1516 Death of Ferdinand II Mar 15, 1516 Charles I of Spain become king Jun 28, 1519 Charles elected Holy Roman Emperor (as Charles V) 1520 Start the Comuneros Revolt in Castile; crushed by Charles Jan 28, 1521 Diet of Worms: Charles condemns Luther May 25, 1521 End the Comuneros Revolt in Castile Feb 24, 1525 Battle of Pavia: Charles defeats Francis I of France May 6, 1527 Sack of Rome by Charles's troops May 21, 1527 Birth of Philip II Jul 19, 1535 Charles conquers Tunis from the Ottomans Sep 25, 1555 Peace of Augsburg 1556 Charles abdicates Philip II (his son) receives Spain, the Netherlands, Naples, and the Americas Ferdinand I (his brother) receives the Holy Roman Empire Aug 10, 1557 Battle of St. Quentin: Spanish victory over France Sep 21, 1558 Charles I of spain/ Charles V DEATH 1561 Philip moved the capital to Madrid May 15, 1568 Beginning of the Dutch Revolt against Spanish rule Sep 7, 1571 – Battle of Lepanto: naval victory over the Ottoman Empire 1580 Iberian Union: Philip becomes King of Portugal 1588 Spanish Armada defeated by England Sep 13, 1598 Death of Philip II; succeeded by Philip III