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Guillermo was born on August 13, 1985.
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“Paco Memo” made his debut in professional soccer in the Mexican First Division on February 15, 2004, in the duel between América and Monterrey, where the capital team won 3 to 2.
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It was not until December 14, in a match against Hungary, that Ochoa played for the national team.
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He is the only Mexican player included in the prestigious list to obtain the 2007 “Golden Ball”
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On January 1, 2011 he was transferred to "AC Ajaccio"