Chapter 3 persecution of the way By lmercer27 60 Great fire of Rome; Nero launches persecutions of Christian’s 70 Destruction of Jerusalem by Titus 81 Persecution under Domitian 88 St. Clement I is Pope; restored the Sacrament of Confirmation according to the rite of St. Peter; martyred in 97 110 St. Ignatius of Antioch martyred 111 Trajan's Rescript in response to Pliny 115 St. Sixtus I is Pope; died in 125 123 Hadrian's Rescript 125 St. Telesphorus is Pope; martyred in 136; He composed the Gloria in Excelsis Deo 153 St. Polycarp martyred 162 St. Justin Martyr dedicates his Second Apology 180 St. Irenæus wntes Against Heresies 193 Tertullian begins writing 203 Sts. Perpetua and Felicity are martyred in the arena at Carthage 215 Origen (ca. 185-254) begins writing 215 Origen (ca. 185-254) begins writing 250 Edict of Decius (emp. 249-251) orders empire-wide persecution of Christians 258 Valerian (emp. 253-260) Rescripts in 257 and 258 284 Diocletian creates the Tetrarchy 304 "Great Persecution" begins under Diocletian 311 Constantine adopts Christian symbol before battie 313 Edict of Milan