History of Pennsylvania By honeybunny Period: Jan 1, 1600 to Oct 4, 2010 Pennsylvania History Oct 24, 1644 William Penn was Born Mar 4, 1681 King Charles II signed the Charter of Pennsylvania Apr 3, 1681 Penn made William Markham (his cousin) deputy governor of the province Jan 1, 1682 Pennsylvania was Founded Jul 19, 1740 An academy that held its first classes became the College of Philadelphia Jul 29, 1755 The college of Philidelphia ultimately grew into the University of Pennsylvania Jan 9, 1765 Philadelphia had been a center of resistance to the Stamp Act Jun 21, 1773 John Penn (the 2nd) became both a Proprietor and the resident executive in Pennsylvania